Universitat de Barcelona
Tumor angiogenesis and vascular patterning: A mathematical model
Tumor angiogenesis is a challeging problem with important consequences for diagnosis and treatment of cancer. Angiogenesis is the process by which new blood vessels grow from existing ones. The idea that a successful establishment of a solid tumor depends on neovascularization has given rise to therapies to deprive the tumor from oxygen and nutrients. However, an optimal therapy requires high resolution imaging to detect the vessels and advanced mathematical models to predict the vascular patterning. In this talk, I will present a multi-scale mathematical model that combines the benefits of a continuous description based on a phase-field model and the capability of tracking individual tip cells.